aspartame (methanol, formaldehyde) -- 740 full text references are
free online -- Woodrow "Woody" C. Monte, retired Prof. of Nutrition,
Arizona State University: Rich Murray 2012.01.03
http://rmforall.blogspot.com/2012/01/new-book-concise-opus-while-science.html
http://health.groups.yahoo.com/group/aspartameNM/message/1631
http://www.amazon.com/While-Science-Sleeps-Woodrow-Monte/dp/1452893675/ref=sr_1_2?ie=UTF8&qid=1325344126&sr=8-2
about 240 pages text, with 740 full text references free online
$ 37.98 paperback -- see:
www.WhileScienceSleeps.com
http://www.amazon.com/review/RNGG3O7U33VCV
Customer Review
life saving facts -- the life work of an earnest, careful, caring,
bold expert, December 30, 2011
By Mr. Richard T. Murray "rmforall"
This review is from: While Science Sleeps (Paperback)
This work is the culmination of a professional lifetime dedicated to
elucidating the key biochemical details of methanol (formaldehyde)
toxicity, starting with a comprehensive warning review in 1984, with
62 references, by the earnest, careful, bold Woodrow "Woody"
C. Monte, retired Prof. of Nutrition, Arizona State University.
He has been sharing his research with me since 1999, including
parts of this masterpiece, as it evolved during the last three years.
Aspartame is indeed 11% methanol (wood alcohol), which the
human body quickly turns into formaldehyde via the ADH enzyme,
concentrated in many tissues: liver, kidney, brain, retina, skin,
muscle, lung, prostate, breast, womb, fetus -- forming cumulative
micro lesions, binding to and disabling DNA, RNA, and proteins,
and so causing a wide variety of symptoms.
Other methanol (formaldehyde) sources include wood and tobacco
smoke, dark wines and liquors, fruits and vegetables heated in
sealed metal and glass containers, and aspartame, as well as a
variety of products ranging from medicines to new carpet, drapes,
and furniture to mobile homes.
People vary enormously in individual vulnerability.
Google "While Science Sleeps" to reach his website, where you
can download for free his 1984 and 2010 reviews, and the final
chapter 12 re birth defects and autism type diseases.
1. Monte WC. Aspartame; Methanol and the Public Health.
Journal of Applied Nutrition 1984;36(1):42-58. 16 pages
586. Monte W. Methanol: A chemical Trojan horse as the root of
the inscrutable U.
Med Hypotheses 2010;74(3):493-6. 4 pages.
Download free Chapter 12 of the book "While Science Sleeps", re
methanol, formaldehyde, birth defects, autism type diseases, with
100 mainstream full text research paper references -- 25 pages.
Then, search Google for other research and news:
Amid health fears, Diet Coke sweetener [aspartame] in safety
spotlight, Sean Poulter, UK Daily Mail 2011.05.27, 141 comments:
Rich Murray 2011.05.30
Pass the good words, friends !
http://www.whilesciencesleeps.com/references/
http://www.whilesciencesleeps.com/While%20Science%20Sleeps%20-%20Chapter%2012%20(ref).pdf
exploring While Science Sleeps at amazon.com: Monte: Murray 2012.01.21
http://www.amazon.com/While-Science-Sleeps-Woodrow-Monte/dp/1452893675/ref=sr_1_2?ie=UTF8&qid=1327205225&sr=8-2
$ 37.98
click on book image on left to Look Inside!
[ at top center, zoom - , zoom + ]
front cover art by Becky Miller -- grieving mother hugs child,
second page, While Science Sleeps art --
depressed science collapsed helpless in bed
as angel waits to offer shining knife of inquiry,
about the author,
table of contents 2 pages,
1-6 start of text,
try random surprise! samples: maybe
25-26,
31-35,
161-164,
217-221 index,
rear cover with charts for USA aspartame sold vs
Alzheimer's deaths ( grew 100 times 1981 to 2000 ) and
autism cases ( grew 2,000 to 140,000 cases 1985 to 1996, adjusted to birth date )
use the search box and enter "multiple sclerosis"
to see a list of 71 results as page numbers and phrases,
with blue color indicating full pages to read,
for instance, Introduction iii-vi, 9-17, 20-21 --
enough to learn quite a lot.
It's really easy to get hooked !
Amid health fears, Diet Coke sweetener [aspartame] in safety
spotlight, Sean Poulter, UK Daily Mail 2011.05.27, 141 comments:
Rich Murray 2011.05.30
http://rmforall.blogspot.com/2011/05/amid-health-fears-diet-coke-sweetener.html
http://health.groups.yahoo.com/group/aspartameNM/message/1625
aspartame water in rats for 6 months causes liver harm,
RH Nair et al, Mahatma Gandhi U, Food Chem Toxicol 2011.03.02:
Rich Murray 2011.03.12
http://health.groups.yahoo.com/group/aspartameNM/message/1620
http://www.ncbi.nlm.nih.gov/pubmed/21376768
Food Chem Toxicol. 2011 Mar 2. [Epub ahead of print]
Effect of long term intake of aspartame on antioxidant defense
status in liver.
Abhilash M, Paul MV, Varghese MV, Nair RH,
School of Biosciences,
Mahatma Gandhi University, Kottayam, Kerala, India, 686560.
harikumarannair@hotmail.com, harinair@fastmail.fm,
careful expert lifetime study on mice shows liver and lung cancers
from aspartame, M Soffritti et al, Ramazzini Institute, Italy, checked
by US National Toxicology Program experts, confirms many
previous studies from 2001 on: Rich Murray 2011.02.27
http://health.groups.yahoo.com/group/aspartameNM/message/1619
re GC Ebers study, females harmed more by body making
methanol into formaldehyde in brain via ADH enzyme:
589 references, WC Monte, retired Prof. Nutrition:
Rich Murray 2011.01.08
http://health.groups.yahoo.com/group/aspartameNM/message/1614
aspartame abstinance cures fibromyalgia chronic pain in 2 French
adults: R Ciappuccini et al, Clin Exp Rheumatol 2010 Nov:
Rich Murray 2010.02.19
http://health.groups.yahoo.com/group/aspartameNM/message/1617
formaldehyde from 0.2 mg daily methanol from aspartame in
Singulair (montelukast) chewable asthma medicine causes severe
allergic dermatitis in boy, SE Jacob et al, Pediatric Dermatology
2009 Nov: Rich Murray 2010.09.27
http://health.groups.yahoo.com/group/aspartameNM/message/1613
http://www.whilesciencesleeps.com/references/
617. Halldorsson T, Strøm M, Petersen S, Olsen S.
Intake of artificially sweetened soft drinks and risk of preterm
delivery: a prospective cohort study of 59,334 Danish pregnant women.
Am J Clin Nutr Doi:10.3945/Ajcn.2009.28968 2010. full text PDF
sweeteners (aspartame), methanol (becomes formaldehyde), and premature
babies in Denmark, TI Halldorsson et al 2010.06.30 AmJClinNutr: Erik
Millstone: Betty Martini: Rich Murray 2010.07.08
http://rmforall.blogspot.com/2010/07/sweeteners-aspartame-methanol-becomes.html
http://health.groups.yahoo.com/group/aspartameNM/message/1609
Am J Clin Nutr. 2010 Jun 30. [Epub ahead of print] 8 pages
Intake of artificially sweetened soft drinks and risk of preterm
delivery: a prospective cohort study of 59,334 Danish
pregnant women.
Halldorsson TI, lur@ssi.dk;
Strøm M, mrm@ssi.dk;
Petersen SB, marp@sund.ku.dk;
Olsen SF. sfolsen@hsph.harvard.edu;
Centre for Fetal Programming, Division of Epidemiology,
Statens Serum Institut, Copenhagen, Denmark, Reykjavik,
Iceland.
Thorhallur I Halldorsson,
Marin Strøm,
Sesilje B Petersen,
and Sjurdur F Olsen
Abstract
BACKGROUND:
Sugar-sweetened soft drinks have been linked to a number
of adverse health outcomes such as high weight gain.
Therefore, artificially sweetened soft drinks are often
promoted as an alternative.
However, the safety of artificial sweeteners has been
disputed, and consequences of high intakes of artificial
sweeteners for pregnant women have been minimally
addressed.
OBJECTIVE:
We examined the association between intakes of
sugar-sweetened and artificially sweetened soft drinks
and preterm delivery.
DESIGN:
We conducted prospective cohort analyses of 59,334
women from the Danish National Birth Cohort (1996-2002).
Soft drink intake was assessed in midpregnancy by using a
food-frequency questionnaire.
Preterm delivery (<37 wk) was the primary outcome measure.
Covariate information was assessed by telephone interviews.
RESULTS:
There was an association between intake of artificially
sweetened carbonated and noncarbonated soft drinks and an increased
risk of preterm delivery (P for trend: 0.001, both variables).
In comparison with women with no intake of artificially
sweetened carbonated soft drinks,
the adjusted odds ratio for women who consumed 1 to 3
serving of artificially sweetened carbonated
soft drinks/d was 1.38 (95% CI: 1.15, 1.65).
The corresponding odds ratio for women who consumed 4 to more
servings of artificially sweetened carbonated
soft drinks/d was 1.78 (95% CI: 1.19, 2.66).
The association was observed for normal-weight and
overweight women.
A stronger increase in risk was observed for early preterm
and moderately preterm delivery than with late-preterm
delivery.
No association was observed for sugar-sweetened
carbonated soft drinks (P for trend: 0.29)
or for sugar-sweetened noncarbonated soft drinks
(P for trend: 0.93).
CONCLUSIONS:
Daily intake of artificially sweetened soft drinks may increase
the risk of preterm delivery.
Further studies are needed to reject or confirm these findings.
PMID: 20592133
1. From the Centre for Fetal Programming,
Division of Epidemiology,
Statens Serum Institut, Copenhagen, Denmark
(TIH, MS, SBP, and SFO);
the Unit for Nutrition Research,
Faculty of Food Science and Nutrition,
School of Health Sciences, University of Iceland (TIH),
Reykjavik, Iceland;
and the Department of Nutrition,
Harvard School of Public Health. Boston, MA (SFO).
2 Supported by the European Union (EU)
Integrated Research Project
EARNEST (FOOD-CT-2005-007036).
The EU project EARNEST
http://www.metabolic-programming.org receives financial
support from the Commission
of the European Communities under the FP 6 priority 5:
food quality and safety.
The Danish National Birth Cohort has been financed by the
March of Dimes Birth Defects Foundation,
the Danish Heart Association,
the Danish Medical Research Council,
and the Sygekassernes Helsefond,
Danish National Research Foundation,
Danish Pharmaceutical Association,
Ministry of Health, National Board of Health,
Statens Serum Institut.
3 Address correspondence to TI Halldorsson,
Centre for Fetal Programming,
Division of Epidemiology, Statens Serum Institut,
Artillerivej 5, Building 206, DK-2300
Copenhagen S, Denmark. E-mail: lur@ssi.dk;
Received November 19, 2009.
Accepted for publication June 3, 2010.
doi: 10.3945/ajcn.2009.28968.
Of the 59,334 pregnant women,
over 4 artificially sweetened
carbonated soft drinks daily __ 340 0.6 %
noncarbonated soft drinks __ 1,753 3.0 %
2-3 cans daily artificially
carbonated _______________ 834 1.4 %
noncarbonated ___________ 3,643 6.1 %
So, over 3% of pregnant women in 1996-2002
used 4 or more artificially sweetened soft drinks daily,
while over 6 % had 2-3 drinks daily.
This does not include aspartame from other foods.
"A monitoring survey from 2005 quantified artificial
sweeteners in 76 soft drinks from the Danish market (30).
For carbonated soft drinks, aspartame and
acesulfame-K were primarily used in products from the
major international brands, and the average concentration of
these 2 sweeteners was around 2--3-fold higher
in carbonated than in noncarbonated soft drinks (30)."
"After ingestion, aspartame is broken down into aspartic acid,
phenylalanine, and methanol.
Methanol is oxidized into formaldehyde and then to
formic acid, which is considered responsible
for the toxic effects of methanol.
Despite arguments that aspartame intake should not affect
blood methanol concentrations (34), animal studies have
reported the accumulation of formaldehyde adducts derived
from aspartame in tissue components (22).
This might be one explaining factor for reports on headaches
linked to the intake of aspartame (10).
More relevant to our findings, a study in low dose methanol
exposure through inhalation in nonhuman primates observed
a significant decrease in the length of gestation in exposed
animals compared with control animals (21).
A shortening of gestation was even observed at methanol
vapor concentrations that barely affected blood methanol
concentrations in these animals (200 ppm; 2.5 h/d).
Furthermore, 5 out of 28 exposed animals needed medical
intervention and were delivered by cesarean delivery either
because of vaginal bleeding (n = 4) or unproductive labor
(n = 1).
None of the 9 control animals required cesarean delivery.
The authors suggested that the observed shortening of
gestation could either be related to the effects of methanol
on the fetal neuroendocrine system
(hypothalamic-pituitary-adrenal axis) or an indirect
action of methanol on the maternal uterine environment.
The latter explanation would be more compatible with our
findings of an increased risk of medically induced preterm
deliveries."
http://whilesciencesleeps.com/references
589 references -- click on each title for free full pdf
http://whilesciencesleeps.com/references/pdf/7
22. Trocho C. Pardo R. Fafecas I. Virgili J. Remesar X.
Fernandez-Lopez. J;
"A.1998. Formaldehyde derived from dietary aspartame
binds to tissue components in vivo", Life Sci 63: 337
http://whilesciencesleeps.com/references/pdf/538
21. Burbacher T, Grant K, Shen D, Sheppard L,
Damian D, Ellis S, et al.; 2004. tmb@u.washington.edu;
"Chronic maternal methanol inhalation in nonhuman primates
(Macaca fascicularis): reproductive performance and
birth outcome.", Neurotoxicol Teratol 26(5):639-50
http://whilesciencesleeps.com/references/pdf/328
10. Jacob SE. Stechschulte S.; 2008
"Formaldehyde, aspartame, and migraines:
a possible connection", Dermatitis 19(3):E10-1
http://whilesciencesleeps.com/references/pdf/544
Abegaz E, Bursey R.; 2009.
"Formaldehyde, aspartame, migraines: a possible connection.
(comment on).", Dermatitis 20(3):176-7.
http://whilesciencesleeps.com/references/pdf/543
Stechschulte S, Jacob S.; 2009.
"Formaldehyde, aspartame, migraines: a possible connection.
(author reply).", Dermatitis 20(3):177-9.
----- Original Message -----
From: "Dr. Betty Martini,D.Hum."
To:
Sent: Thursday, July 08, 2010 11:19 AM
Subject: Fwd: Sweeteners, methanol and
premature deliveries - new study
Dear Erik,
Thank you so much.
Of course, fetal tissue does not tolerate methanol and
aspartame triggers birth defects and mental retardation.
http://www.rense.com/general/asp.htm
Interestingly, in restaurants so many times you see these
signs, "If you're pregnant, don't use alcohol -- can cause birth
defects".
If just alcohol is known to cause birth defects, anyone of
intelligence knows that methanol or wood alcohol, a severe
metabolic poison, would be worse.
Then you have the phenylalanine
www.mpwhi.com/louis_elsas_testifying_to_congress.htm
Yet, government agencies refuse to put a warning for
pregnant women.
There is only a PKU warning.
Big Pharma still runs government agencies.
I remember about 15 years ago I spoke with somebody
who worked for Monsanto and was told one of their people
said, "When we say something the FDA jumps. They do
what we say!"
So innocent babies are born autistic, with Tourettes, mentally
retarded and more, because the FDA are cowards,
and the manufacturers are criminals.
Glad to see this.
All my best, Betty
www.mpwhi.com
www.dorway.com
www.wnho.net
Aspartame Toxicity Center www.holisticmed.com/aspartame
Subject: Sweeteners, menthanol and premature deliveries
Originator-Info: login-id=mhfa1; server=mail.sussex.ac.uk;
token_authority=http://www.sussex.ac.uk/its/help/support.php
Dear Jim and colleagues
Please find attached a copy of a paper that has just come out
in the American Journal of Clinical Nutrition.
It is a huge study of Danish women, indicating that women
who consumed artificially sweetened beverages were
significantly more likely than women who consumed
sugar-sweetened to have premature deliveries of their
babies.
You will be interested in particular because they suggest
that methanol may be implicated in an underlying mechanism
This may therefore be grist to your mill,
with best wishes from Erik
Prof Erik Millstone
SPRU - Science and Technology Policy Research
Freeman Centre
University of Sussex
Brighton BN1 9QE, ENGLAND
Phone +44 (0)1273 877380
See 'Can Science and Politics help keep each other honest?'
Professorial Lecture 11 May 2010,
available at
See recent Professorial Lecture at the University of Sussex on
'Can Science and Politics help keep each other honest?',
11 May 2010 available at
www.sussex.ac.uk/newsandevents/sussexlectures/2010.php
[ Adequate folic acid protects most mothers from having
children with birth defects from methanol and
its products in their bodies, formaldehyde and formic acid. ]
Food Nutr Bull. 2008 Jun;29(2 Suppl):S205-9.
Folic acid for the prevention of neural tube defects:
the Danish experience.
Olsen SF, Knudsen VK.
Maternal Nutrition Group, Division of Epidemiology,
Statens Serum Institut, Copenhagen, Denmark.
sfolsen@hsph.harvard.edu;
Abstract
Evidence from controlled trials suggests that ingestion of
0.4 mg of folic acid per day in the periconceptional period
is effective in preventing neural tube defects (NTD).
For this reason, most countries recommend that women
planning pregnancy take folic acid supplements in the
periconceptional period, and some countries even fortify
stable foods with folic acid.
Denmark exemplifies a country with a relatively conservative
attitude with respect to taking action in these matters.
In 1999, a national information campaign was launched that
recommended women planning pregnancy take 0.4 mg of
folic acid periconceptionally, but with the moderation that
women who eat a healthy diet do not need to take folic acid
supplement.
The campaign was repeated during 2001.
The results of the latter campaign were evaluated by using
data from a national survey among pregnant women
conducted simultaneously with the campaign by the
Danish National Birth Cohort.
An increase in the proportion of folic acid users took place
concomitantly with the launching of the information events,
but the increase was limited.
Among women who did not plan their pregnancy, a small
proportion had taken folic acid supplements
periconceptionally, and this proportion did not change
concomitantly with the campaign.
Young age and low education were factors associated
with low likelihood of taking folic acid.
It seems that different and more efficient actions are
needed if a more substantial proportion of Danish women
and their fetuses are going to benefit from the knowledge
that folic acid supplementation in the periconceptional
period can prevent NTD.
PMID: 18709894
Rich Murray,
MA Boston University Graduate School 1967 psychology,
BS MIT 1964 history and physics,
254-A Donax Avenue, Imperial Beach, CA 91932
rmforall@gmail.com
505-819-7388
Skype audio, video rich.murray11
http://RMForAll.blogspot.com
new primary archive
http://health.groups.yahoo.com/group/aspartameNM/messages
group with 120 members, 1,631 posts in a public archive
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group with 1,235 members, 24,405 posts in a public archive
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